English to Russian Science Biology (-tech,-chem,micro-)

In some aspects, the antigen-binding construct described herein comprises ""a heterodimeric Fc"" comprising a modified CH3 domain that has been asymmetrically modified. The heterodimeric Fc can comprise two heavy chain constant domain polypeptides: a first Fc polypeptide and a second Fc polypeptide, which can be used interchangeably provided that ""Fc"" comprises one first Fc polypeptide and one second Fc polypeptide. Generally, the first Fc polypeptide comprises a first CH3 sequence and the second Fc polypeptide comprises a second CH3 sequence.

Two CH3 sequences that comprise one or more amino acid ""modifications introduced in an asymmetric fashion"" generally results in a ""heterodimeric Fc"", rather than a homodimer, when the two CH3 sequences dimerize


что такое heterodimeric Fc? Fc-домен?
Fc-фрагмент? Fc-область.

Название раздела: Fc of antigen-binding constructs. просто Fc

Спасибо!