Glossary entry (derived from question below)
English term or phrase:
parasite solute and drug transporter
Russian translation:
транспортный мембранный белок/транспортер растворенных веществ и лекарственных препаратов у паразитов
Added to glossary by
Margarita Vidkovskaia
Aug 13, 2020 14:50
3 yrs ago
16 viewers *
English term
Russian Federation
parasite solute
English to Russian
Medical
Medical (general)
Инфекционные болезни
The mechanism of resistance to this drug has been pinpointed to mutations affecting an aquaglyceroporin (AQP2), a parasite solute and drug transporter.
Контекст: развитие резистентности к меларсопролу.
Контекст: развитие резистентности к меларсопролу.
Proposed translations
(Russian)
| 4 +1 | см. |
Margarita Vidkovskaia
|
Change log
Aug 14, 2020 18:58: Margarita Vidkovskaia Created KOG entry
Proposed translations
+1
8 hrs
Margarita Vidkovskaia
Russian Federation
Russian Federation
Native in Russian
Specializes in field
Russian Federation
MD, Medicine & Clinical Research
Native in: Russian 
Works in: English to Russian
Related KudoZ points
:
1396
Selected
см.
акваглицеропорин (AQP2), ***мембранный транспортный белок/транспортер растворенных веществ и лекарственных препаратов у паразитов***
aquaglyceroporin (AQP2), a ***parasite solute and drug transporter***
aquaglyceroporin (AQP2), a ***parasite solute and drug transporter***
4 KudoZ points awarded for this answer.
Reference comments
8 hrs
Reference:
"Aquaglyceroporins (AQPs) transport water and glycerol and play important roles in drug-uptake in pathogenic trypanosomatids. For example, AQP2 in the human-infectious African trypanosome, Trypanosoma brucei gambiense, is responsible for melarsoprol and pentamidine-uptake, and melarsoprol treatment-failure has been found to be due to AQP2-defects in these parasites".
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388498/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388498/
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