HR

Russian translation: high-risk

15:23 Jan 12, 2022
English to Russian translations [PRO]
Medical - Medical (general)
English term or phrase: HR
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Main focus for X (компания) has shifted from RR to FL with the GMMG-HD7 results, and experts see this study confirming the need of quadruplets upfront. Results of GMMG-HD7, with MRD as a co-primary endpoint, show the highest MRD negativity rate after induction in TE NDMM. However, due to study design of duo primary endpoints, X cannot file for regulatory approval until the other co-primary endpoint (PFS after 2nd randomization) is met.

X continues to differentiate focusing on high unmet need subgroups for RR, including HR with gain 1q abnormality.

Во фразе " including HR" - HR - high risk или hazard ratio?

Спасибо.
Nadezhda Wenzel
Russian translation:high-risk
Explanation:
https://pubmed.ncbi.nlm.nih.gov/32750129/
A gain in 1q was found in 391 patients (28%) and was associated with anemia, hypercalcemia, high tumor burden, International Staging System (ISS) stage 3, high-risk (HR) translocations, and chromosome 13 abnormalities.

There is an unmet treatment need, particularly among patients with poor prognoses,
including those with high-risk cytogenetics,
Selected response from:

hawkwind
Russian Federation
Local time: 03:23
Grading comment
Благодарю.
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +1hazard ratio
interprivate
4high-risk
hawkwind


  

Answers


1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
hr
hazard ratio


Explanation:
...

interprivate
Local time: 18:23
Native speaker of: Native in RussianRussian, Native in UkrainianUkrainian
PRO pts in category: 243

Peer comments on this answer (and responses from the answerer)
agree  Erzsébet Czopyk
5 hrs
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8 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
hr
high-risk


Explanation:
https://pubmed.ncbi.nlm.nih.gov/32750129/
A gain in 1q was found in 391 patients (28%) and was associated with anemia, hypercalcemia, high tumor burden, International Staging System (ISS) stage 3, high-risk (HR) translocations, and chromosome 13 abnormalities.

There is an unmet treatment need, particularly among patients with poor prognoses,
including those with high-risk cytogenetics,

hawkwind
Russian Federation
Local time: 03:23
Works in field
Native speaker of: Native in RussianRussian
PRO pts in category: 546
Grading comment
Благодарю.
Login to enter a peer comment (or grade)



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