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Russian translation: здесь: за счет покрывающей ее двойной натуральной защитной пленки
| 20:29 Apr 28, 2023 |
| English to Russian translations [PRO] Medical - Medical: Pharmaceuticals | |||||
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|  Selected response from: Evgeni Kushch Ukraine Local time: 15:30 | ||||
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| 3 | здесь: за счет покрывающей ее двойной натуральной защитной пленки |
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21 mins confidence: 
здесь: за счет покрывающей ее двойной натуральной защитной пленки Explanation: Бактерия самостоятельно формирует споры, обладает резистентностью к высокой температуре и давлению, используемым в процессе производства продуктов, за счет покрывающей ее двойной натуральной защитной пленки, а также демонстрирует отличные показатели выживаемости в кишечнике за счет резистентности к воздействию кислоты. -------------------------------------------------- Note added at 28 mins (2023-04-28 20:58:04 GMT) -------------------------------------------------- Toxicity The evaluation of a strain's safety and probiotic qualities are required for human and animal uses. Heat resistance, lysozyme resistance, biofilm formation, cell aggregation properties, pH levels, bile salt concentrations, antibacterial activity, antibiotic resistance, metabolic activity, and toxicological characteristics are the main criteria for probiotic organism selection.14,48 Здесь можно загрузить статью, там упоминается формирование биопленки: https://www.researchgate.net/publication/364308646_Bacillus_... -------------------------------------------------- Note added at 36 mins (2023-04-28 21:06:21 GMT) -------------------------------------------------- In most natural ecosystems, bacteria prefer to grow in a complex community of multicellular cells, called biofilm, and not as free-living (planktonic) cells. The biofilm mode of growth also is preferable for bacteria that inhabit the intestinal tract [Citation9]. Cells in a biofilm are bound together by an extracellular matrix that consists mainly of polysaccharides and other macromolecules, such as proteins, DNA, lipids, and nucleic acids, which are produced by the cells themselves [Citation10]. Interactions between the species embedded in the biofilm and their environment result in the formation of complex structures, capable of resisting environmental stress and exposure to antimicrobial agents [Citation11]. Thus, biofilm formation represents a strategy for persistence under unfavorable conditions in diverse environments, such as those encountered during passage through the gastrointestinal tract (GIT) of mammals. https://www.tandfonline.com/doi/full/10.1080/21691401.2018.1... -------------------------------------------------- Note added at 37 mins (2023-04-28 21:07:35 GMT) -------------------------------------------------- The development of a biofilm constitutes a survival strategy by providing bacteria a protective environment safe from stresses such as microbicide action and can thus lead to important health-care problems. In this study, biofilm resistance of a Bacillus subtilis strain (called hereafter NDmedical) recently isolated from endoscope washer-disinfectors to peracetic acid was investigated and its ability to protect the pathogen Staphylococcus aureus in mixed biofilms was evaluated. Biocide action within Bacillus subtilis biofilms was visualised in real time using a non-invasive 4D confocal imaging method. The resistance of single species and mixed biofilms to peracetic acid was quantified using standard plate counting methods and their architecture was explored using confocal imaging and electronic microscopy. The results showed that the NDmedical strain demonstrates the ability to make very large amount of biofilm together with hyper-resistance to the concentration of PAA used in many formulations (3500 ppm). Evidences strongly suggest that the enhanced resistance of the NDmedical strain was related to the specific three-dimensional structure of the biofilm and the large amount of the extracellular matrix produced which can hinder the penetration of peracetic acid. When grown in mixed biofilm with Staphylococcus aureus, the NDmedical strain demonstrated the ability to protect the pathogen from PAA action, thus enabling its persistence in the environment. This work points out the ability of bacteria to adapt to an extremely hostile environment, and the necessity of considering multi-organism ecosystems instead of single species model to decipher the mechanisms of biofilm resistance to antimicrobials agents. https://journals.plos.org/plosone/article?id=10.1371/journal... -------------------------------------------------- Note added at 39 mins (2023-04-28 21:09:06 GMT) -------------------------------------------------- или дословно: за счет окружающей ее двойной натуральной защитной пленки |
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