Caro Pinitol
Russian translation: пинитол в составе экстракта рожкового дерева
| 13:32 Apr 29, 2023 |
| English to Russian translations [PRO] Medical - Medical (general) | |||||
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|  Selected response from: Evgeni Kushch Ukraine Local time: 00:08 | ||||
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| 3 +1 | пинитол в составе экстракта рожкового дерева |
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11 mins confidence: 
peer agreement (net): +1
peer agreement (net): +1| caro pinitol пинитол в составе экстракта рожкового дерева Explanation: Предположу, что, возможно, имеется в виду carob: https://www.google.com.ua/search?q=экстракт рожкового дерева... -------------------------------------------------- Note added at 13 mins (2023-04-29 13:45:50 GMT) -------------------------------------------------- Carob is one of the major food trees for peoples of the Mediterranean basin, but it has also been traditionally used for medicinal purposes. Carob contains many nutrients and active natural products, and D-Pinitol is clearly one of the most important of these. D-Pinitol has been reported in dozens of scientific publications and its very diverse medicinal properties are still being studied. Presently, more than thirty medicinal activities of D-Pinitol have been reported. Among these, many publications have reported the strong activities of D-Pinitol as a natural antidiabetic and insulin regulator, but also as an active anti-Alzheimer, anticancer, antioxidant, and anti-inflammatory, and is also immune- and hepato-protective. In this review, we will present a brief introduction of the nutritional and medicinal importance of Carob, both traditionally and as found by modern research. In the introduction, we will present Carob’s major active natural products. The structures of inositols will be presented with a brief literature summary of their medicinal activities, with special attention to those inositols in Carob, as well as D-Pinitol’s chemical structure and its medicinal and other properties. D-Pinitol antidiabetic and insulin regulation activities will be extensively presented, including its proposed mechanism of action. Finally, a discussion followed by the conclusions and future vision will summarize this article. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003036/ -------------------------------------------------- Note added at 15 mins (2023-04-29 13:47:25 GMT) -------------------------------------------------- D-pinitol is a natural compound related to the important family of inositols. It can be found and isolated from many plants, being the active component of ayurvedic remedies such as Talisa patra (Abies webbiana, A. pindrow) or antidiabetic as Bougainvillea (Bougainvillea spectabilis). Although many synthetic and semi-synthetic methods have been reported for D-pinitol and its derivatives, through chemical and biochemical transformations, Ceratonia siliqua L. (Carob), a Mediterranean tree now in decline, known because of its environmental advantages, is the only raw material from which D-pinitol can be isolated in quantities enough for a viable commercial exploitation. Fortunately, the pharmacological interest in this compound has risen enormously in the last years owing to their established multifunctional properties through a variety of signalling pathways: i) anti-cancer, through inhibition of TNF-ᾳ and suppression of NF-ⱪB pathway; ii) insulinomimetic and metabolic regulator in type 2 diabetes mellitus, via a post-receptor pathway of insulin action; iii) antioxidant; iv) hepatoprotective; v) immuno-modulator, balancing Th1/Th2 cytokines; vi) osteoporosis preventive, through p38/JNK and NF-ⱪB pathways; vii) anti-aging, via reduction of the insulin/IGF-1 signaling (IIS) pathway; viii) improver of creatine retention; ix) preventive and ameliorative of Alzheimer’s disease through selective g-secretase modulation. Thus, the present review compress the literature reported to date in relation to the health-promoting effects and metabolic pathways of this naturally occurring super-food ingredient and its derivatives, providing an extensive guide for a future utilization of all of its potentialities, aiming a positive impact in the promotion and recovery of carob crops. Или: пинитол, полученный из рожкового дерева -------------------------------------------------- Note added at 15 mins (2023-04-29 13:47:49 GMT) -------------------------------------------------- https://www.researchgate.net/publication/323429733_D-pinitol... -------------------------------------------------- Note added at 18 mins (2023-04-29 13:50:25 GMT) -------------------------------------------------- Хотя вот здесь нашел наименование зарегистрированного продукта Caro pinitol®, судя по всему: Vegetable soybean (Glycine max) is well established legume in the human diet in all over the world. D-Pinitol is a natural product belonging to groups of Cyclitols. D-pinitol plays tremendous medicinal roles. The aim of this work is to quantify the bioactive constituent D-Pinitol from seeds, seed pods and leaves of soybean. D-Pinitol extraction of soybean was processed with methanolic extraction followed by quantification using a UV spectrophotometer in comparisons with the Caro pinitol®. The maximum wavelength and absorbance of the standard dissolved in laboratory reagent water were 193 nm and 0.904 respectively. The best-fit line, R2, was found to be greater than 0.9983, indicating the D-pinitol’s concentration has significant effect on D-pinitol’s absorbance over a concentration range of 31.25-1000.0 μg/mL. The mean recovery of the method was 94.3 ± 8.06%. The absorbance of the serially diluted standard of 31.25 μg/nL, 62.5 μg/mL, 125 μg/mL, 250 μg/mL, 500 μg/L and 1000 μg/mL at 193 nm is 0.032, 0.042, 0.096, 0.205, 0.375, and 0.714, respectively. The absorbance of the samples Nyala seed (so), Nyala seed (mz), Nova seed (so), Nova seed (mz), Nyala seed pod (so), Nova seed pod (so), Nyala leaf (so) and Nova leaf (so) at 193 nm were 0.237, 0.267, 0.307, 0.204, 0.213, 0.276, 0.24 and 0.263, respectively. The quantity (gm) of D-pinitol within 25 gm crude extract of Nyala seed (so), nyala seed (mz), nova seed (so), nova seed (mz), nyala seed pod (so), nova seed pod (so), nyala leaf (so) and nova leaf (so) were 16.2, 18.4, 21.3, 13.9, 14.5, 19, 16.5 and 18.1, respectively. The quantitative values of all varieties are closer to each other and this may be attributed to the similarity between the sampling areas, South Omo and Metekel zone. Generally, the Ethiopian soybean has high Dpinitol content. The pairwise comparison using the Student’s t-test shows no significant difference, p>0.05, between the content of D-pinitol in seed, seed pod and leaf. https://www.iomcworld.com/abstract/quantification-of-bioacti... -------------------------------------------------- Note added at 27 mins (2023-04-29 13:59:07 GMT) -------------------------------------------------- Вот здесь написано, что это все тот же D-пинитол, и как синоним Caro Pinitol P, тогда, возможно, просто транслитерировать как Каро пинитол, не знаю только, прислать слитно или раздельно, надеюсь, коллеги поправят, если в эту сторону вообще. Synonyms: 3-O-Methyl-D-chiro-inositol(+)-Pinitol(1R,2S,3R,4S,5S,6S)-6-methoxycyclohexane-1,2,3,4,5-pentol(1R,2S,3r,4R,5S,6r)-6-methoxycyclohexane-1,2,3,4,5-pentol(1R,2S,4S,5S)-6-methoxycyclohexane-1,2,3,4,5-pentol3-O-Methyl-(+)-chiro-inositol3-O-Methyl-D-chiro-inositol6-Methoxycyclohexane-1,2,3,4,5-PentolD-(+)-PinitolD-3-O-Methyl-chiro-inositolD-chiro-Inositol, 3-O-methyl-Caro Pinitol PD-chiro-Inositol, 3-O-methyl-D-chiro-Inositol, 3-O-methyl- (9CI)Inositol, 3-O-methyl-, D-chiro-Inositol, 3-O-methyl-, D-chiro- (8CI)InzitolMatezitNsc 128700Nsc 43336PinitPinite (inositol derivative)Pinitol BSennitSennitol CAS: https://cymitquimica.com/products/3B-P2219/10284-63-6/d-pini... |
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