15:39 Aug 21, 2023 |
English to Russian translations [PRO] Medical - Medical: Pharmaceuticals / clinical trials | |||||||
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| Selected response from: cherepanov Ukraine Local time: 20:48 | ||||||
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3 | суспензия стволовых клеток эпителия кишечника |
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3 | базовый фекальный раствор |
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суспензия стволовых клеток эпителия кишечника Explanation: Не стоит переводить solution как "раствор" - клетки суспендированы, а не растворены, слишком велики для образования истинных растворов. https://repo.odmu.edu.ua/xmlui/bitstream/handle/123456789/13... ...3) крысы с модельным паркинсонизмом, которым с лечебной целью одноразово внутривенно вводи-ли 0,5 мл суспензии стволовых клеток в дозе 2×10 6 на 1 крысу. https://studfile.net/preview/9830912/page:17/ ...Эти данные свидетельствуют, что восстановление эпителиального слоя слизистой оболочки у выживших животных протекает очень быстро, а пул стволовых клеток кишечного эпителия в этот период находится на стадии гиперрегенерации |
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базовый фекальный раствор Explanation: базовый (основной) фекальный раствор Это раствор, приготовленный из фекальных масс, вводимый (без дальнейшего разведения) внутрибрюшинно для индукции перитонита. https://pubmed.ncbi.nlm.nih.gov/22523283/ Male C57BL/6 mice (weight 25–30 g, age 8 wk) were obtained from Jackson Laboratory (Bar Harbor, ME). Polymicrobial sepsis (peritonitis) was induced by intraperitoneal (i.p.) introduction of fecal stem solution into the peritoneum (FIP). Fecal stem solution was prepared by a modification of the method reported by Bernardshaw et al. (8). Dry fecal pellets were randomly collected from all the mice-containing cages 1 day before the challenge. Weighed pellets (70 pellets 1 g) were pooled and suspended in saline (180 mg feces/1 ml saline). The solution was capped tightly, vortexed for 5 min, and stored overnight at 4°C. The mixture was then allowed to return to room temperature and solids were compacted by low-speed centrifugation (50 g) for 5 min. The recovered supernatant was termed fecal stem solution. Этот базовый (основной) раствор может вводиться в разведениях, как у Bernardshaw et al. (8) https://pubmed.ncbi.nlm.nih.gov/16670646/ Preparation of Standard Fecal Solution The inoculum was made by pooled dry fecal pellets that were randomly collected from all the mice-containing cages 1 day before the challenge. Within 30 min of challenge, 10 mL of pooled pellets, weighing 4.0 T 0.5 g, were mixed with 30 mL of PBS at room temperature. The mixture was thoroughly shaken before filtering through a double layer of surgical gauze with a mesh diameter of 1 to 2 mm. This stem solution was defined as the undiluted fecal inoculum (1/1). Further dilutions were made by adding PBS. |
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