activating EGFR gene mutations

Russian translation: активирующие мутации в гене EGFR

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)

English term or phrase:	activating EGFR gene mutations
Russian translation:	активирующие мутации в гене EGFR
Entered by:	Elene P.

05:28 Nov 23, 2016

English to Russian translations [PRO]
Medical - Medical (general)

English term or phrase: activating EGFR gene mutations

что активируется?
мутации активирующие ген?
генные мутации активирующие EGFR ?
активирование мутаций гена EGFR ?

Third, without known activating EGFR gene mutations or ALK gene translocations.

спасибо и с праздником Св. Георгия :)

Elene P.
Georgia

активирующие мутации в гене EGFR

Explanation:
См. ссылку.

Selected response from:

Alla Lugakova
Poland
Local time: 10:33

Grading comment

спасибо
4 KudoZ points were awarded for this answer

Summary of answers provided

3 +2

активирующие мутации в гене EGFR

Alla Lugakova

4 +1

см.

Margarita Vidkovskaia

Answers

42 mins confidence:

peer agreement (net): +2

activating egfr gene mutations

активирующие мутации в гене EGFR

Explanation:
См. ссылку.

Reference: http://biolinklab.ru/analiz-mutacii-v-gene-egfr-pri-rake-leg...

Alla Lugakova
Poland
Local time: 10:33
Specializes in field
Native speaker of:

Russian,

Belarusian
PRO pts in category: 12

Grading comment

спасибо

2 hrs confidence:

peer agreement (net): +1

activating egfr gene mutations см.

Explanation:
В третьих, не наблюдалось известных активирующих мутаций гена рецептора эпидермального фактора роста (epidermal growth factor receptor, EGFR) и транслокаций гена киназы анапластической лимфомы (anaplastic lymphoma kinase, ALK).

There are two types of mutation.
Activating mutation causes the gene to be expressed at the wrong time at the wrong level or even with a new function. So this means that activating in oncogenes are tumorigenic.
Their converse are inactivating mutations, and these cause reduced function of a gene. So either less RNA, or protein is made. The inactivating mutations in tumor suppressors are tumorigenic.

Margarita Vidkovskaia
Russian Federation
Local time: 11:33
Specializes in field
Native speaker of:

Russian
PRO pts in category: 1396

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activating EGFR gene mutations

Russian translation: активирующие мутации в гене EGFR

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activating EGFR gene mutations

Russian translation: активирующие мутации в гене EGFR

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